Volume 6, Issue 2 (6-2024)                   alkhass 2024, 6(2): 1-9 | Back to browse issues page


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Sedaghat H, Chaboki M, Esmaeilzadeh M. Berberine: Structure, Applications, Efficacy, and Recent Achievements. alkhass 2024; 6 (2) :1-9
URL: http://alkhass.srpub.org/article-4-215-en.html
IR_TAK_41/796234, Development, Economy and Entrepreneurship Holding (TAK) Tehran, Iran
Abstract:   (147 Views)
Berberine, a natural isoquinoline alkaloid, has attracted considerable attention for its diverse pharmacological properties. Extracted from plants like “Berberis” species and “Coptis chinensis”, berberine has been used in traditional medicine systems for centuries. Modern research has unveiled its significant potential in managing metabolic syndromes, cardiovascular disorders, microbial infections, and cancer. This review provides an in-depth analysis of berberine’s mechanisms of action, therapeutic applications, clinical efficacy, and safety profile. Although promising, challenges such as low bioavailability and limited high-quality clinical trials need to be addressed to realize its full potential.
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Type of Study: Applicable | Subject: Nutraceuticals and functional foods
Received: 2024/03/10 | Revised: 2024/04/15 | Accepted: 2024/05/23 | Published: 2024/06/25

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